8 Comments
Jan 13, 2021Liked by Kelly Fradin, MD

Thank you for this post! It helped answer any concerns I had as I have young children that more than likely won’t get vaccinated this year.

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You listed prematurity as a risk factor. Is that only while the child is a premie or if the child is older but was born prematurely? My son is 28 months and healthy, born at 36.5 weeks. Thanks!

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author

Hi! So the prematurity risk factor isn’t well delineated yet but I have estimated that children who struggle with other viruses (like hospitalized with) due to chronic lung disease may be more affected with covid too. This is more common closer to 32 weeks.

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Jan 13, 2021Liked by Kelly Fradin, MD

Thank you very much for your reply. He was hospitalized with RSV at 9 weeks but hasn’t been diagnosed with a chronic lung disease. We do have a hx of asthma in our family though. It is a lot to take in and process. I really appreciate your efforts to educate!

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Any info about how long immunity lasts from any of the vaccines? I asked several docs a month or so ago, and they said "3 months is all we know" which is so depressing. Also, any info on about how long immunity lasts after recovering from the virus? Is it longer than 3 months? (which is what my local health dept says) And....if there isn't concrete evidence yet for the above questions, what might be your best guess?

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author

Excellent question. This is a remarkably complex question because our immune system has so many components (we can look quickly at antibodies as a proxy but there are memory b cells that produce antibody on demand which are harder to look at). 3 months is very solidly known / definite based on the data from the vaccine trials and how people react after infection. I would expect a minimum of a year of full strength immunity, but it could be longer, based on other vaccines, even if it does begin to wane after a year, it's likely that it will offer some protection and still give a benefit (ie. make the illness more mild if you do get it).

I was just reading this article, which is quite technical but goes into a lot of detail and backs up the fact that after infection individuals are highly likely to have complete immunity for 8 months. Though of course we could have new variants emerge to elude this they haven't yet. https://science.sciencemag.org/content/sci/early/2021/01/06/science.abf4063.full.pdf

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"The vaccines seem to prevent about 95% of severe infections from COVID-19 and after the first dose of moderna the risk of being an asymptomatic carrier of COVID-19 decreases by nearly 60%."

Do we have any data on the Pfizer vaccine and risk of being an asymptomatic carrier? Thank you!

Rachel K.

Houston, TX

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Thanks for asking. No data from the Pfizer one yet, though every expectation that it will be similar. Someone else asked, here is the citation for the Moderna 60% number. https://www.fda.gov/media/144453/download

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